In macular hole, a hole occurs in the middle of the retina. This leads to a pronounced loss of vision, which increases with time. With modern surgical procedures, the hole can be closed in over 90% of cases. The diagnosis is made by examination by the specialist and optical coherence tomography. The procedure includes removal of the vitreous body (vitrectomy) by means of minimally invasive surgery, peeling of the inner limiting membrane of the retina and a gas filling. Due to the complexity of the procedure and to monitor possible complications, the procedure is performed as an in-patient procedure. With specialized and internationally trained retinal surgeons, the University Clinic of Ophthalmology has state-of-the-art equipment for the optimal treatment of macular holes.