Age-related macular degeneration (AMD) is the leading cause of legal blindness in the industrial world in people over an age of 65 years. Our research is therefore focused on cause and mechanisms of the observed defects as well as on the development of new therapeutic and diagnostic strategies. The following projects depict the main research area of Experimental Ophthalmology.
Teamleiter Prof. Dr. V. Enzmann
- Conedera F, Quintela Pousa AM, Tschopp M, Mercader N, Enzmann V: Retinal microglia signaling affects Müller cell behavior in the zebrafish following laser injury induction. Glia. 67(6):1150-1166, 2019.
- Conedera FM, Arendt P, Trepp C, Tschopp M, Enzmann V: Müller Glial Cell Activation in a Laser-Induced Retinal Degeneration and Regeneration Model in Zebrafish. J Vis Exp. 128: e56249, 2017.
- Enzmann V, Lecaudé S, Kruschinski A, Vater A: CXCL12/SDF-1-dependent retinal migration of endogenous bone marrow-derived stem cells improves visual function after pharmacologically induced retinal degeneration. Stem Cell Rev 13(2): 278-286, 2017.
- Reisenhofer M, Balmer J, Enzmann V: What can pharmacological models of retinal degeneration tell us? Cur. Mol. Med. 17(2): 100-107, 2017.
- Mathivanan I, Trepp C, Brunold C, Baerlocher G, Enzmann V. Retinal differentiation of human bone marrow-derived stem cells by co-culture with retinal pigment epithelium in vitro. Exp Cell Res. 333(1):11-20, 2015.