"Fluorescence lifetime imaging ophthalmoscopy, FLIO, has emerged as an innovative imaging technique within the field of ophthalmology. In contrast to other retinal imaging modalities, which provide detailed structural information with increasing spatial resolution and depth, FLIO has been shown to provide contrast for macular pigment and photoreceptors, and possibly provides information about metabolic changes occurring in the retina before structural changes can be seen in conventional imaging modalities. As such, FLIO may provide information about viability of photoreceptors and the retinal pigment epithelium, and therefore supplement other imaging modalities."